Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Injectable SF-platform orchestrates GPX4-targeted ferroptosis-autophagy-immunogenic circuit for overcoming oxidative resistance in triple-negative breast cancer

11 Aug 2025

Abstract excerpt

The injectable SF platform, incorporating sequential therapeutic modules, demonstrates potent anti-tumor efficacy and holds significant promise for clinical translation in the treatment of TNBC.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40963899
DOI: 10.7150/thno.116013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Injectable SF-platform orchestrates GPX4-targeted ferroptosis-autophagy-immunogenic circuit for overcoming oxidative resistance in triple-negative breast cancerPMID 40963899Read ↗

Huaier Polysaccharides Targets Cancer Stem Cells in Triple-Negative Breast Cancer via ASM-mediated Autophagy-dependent FerroptosisSemantic proximity Read ↗

Ferroptosis assassinates tumor (FAST)Semantic proximity Read ↗

A novel taxane SB-T-101141 triggers a noncanonical ferroptosis to overcome Paclitaxel resistance of breast cancer via iron homeostasis-related KHSRPSemantic proximity Read ↗

Nanotechnology-integrated ferroptosis inducers: a sharp sword against tumor drug resistanceSemantic proximity Read ↗

Targeting GPX4 in human cancer: Implications of ferroptosis induction for tackling cancer resilienceSemantic proximity Read ↗

Targeting ferroptosis: a promising strategy to overcome drug resistance in breast cancerSemantic proximity Read ↗

Ferroptosis by nanomaterials: targeting cancer stem cells and overcoming drug resistanceSemantic proximity Read ↗

Taraxerol induces ferroptosis in breast cancer by targeting Nrf2 transcriptional activity to promote MIB2-mediated GPX4 ubiquitinationSemantic proximity Read ↗

Single-cell morphological and transcriptome analysis unveil inhibitors of polyploid giant breast cancer cells in vitroSemantic proximity Read ↗

GPX4-VIM equates a proliferating DTP state in TNBC subtypes with converged vulnerabilities to autophagy and glutathione inhibitionSemantic proximity Read ↗

A chiral fluorescent Ir( iii ) complex that targets the GPX4 and ErbB pathways to induce cellular ferroptosisSemantic proximity Read ↗

PNKP targeting engages the autophagic machinery through STING and STAT3 to potentiate ferroptosis and chemotherapy in TNBCSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.