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Article

Genomic analysis of lean individuals with NAFLD identifies monogenic disorders in a prospective cohort study

2 Feb 2023

Abstract excerpt

Background & Aims: Lean patients with non-alcoholic fatty liver disease (NAFLD) represent 10-20% of the affected population and may have heterogeneous drivers of disease. We have recently proposed the evaluation of patients with lean NAFLD without visceral adiposity for rare monogenic drivers of disease. Here, we aimed to validate this framework in a well-characterised cohort of patients with biopsy-proven NAFLD...

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Share to Diabetes, Cardiovascular Risks, and Lipoproteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36937991
DOI: 10.1016/j.jhepr.2023.100692

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