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Article

Phenotypic age acceleration as a novel predictor of benign prostatic hyperplasia: a prospective cohort study.

GeroScience - 1 Jun 2026

Li Xuwen, Lian Penghu, Chen Hongyan, Zhang Liangzhe, Zhang Zhe, Wang Jing, Xing Nianzeng, Jiang Tao, Chen Ziwei, Zhang Xinlei, Ye Xiongjun

Abstract excerpt

This study aims to investigate the predictive value of combined phenotypic age and phenotypic age acceleration (PhenoAgeAccel) for benign prostatic hyperplasia (BPH) and develop a machine learning-based risk prediction model to inform precision prevention and clinical management strategies. The study analyzed data from 784 male participants in the US National Health and Nutrition Examination Survey (NHANES,...

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Identifiers

PMID: 40931290
DOI: 10.1007/s11357-025-01846-9
PMCID: PMC13356109

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