Dietary antioxidants: a challenge or an opportunity for asthma? Genetic insights from a Two-sample mendelian randomization study.

doi:10.1080/02770903.2025.2555297

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Article

Dietary antioxidants: a challenge or an opportunity for asthma? Genetic insights from a Two-sample mendelian randomization study.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Dec 2025

Zhou Xiaoqing, Zhou Yujie, Chen Jialing, Chen Chen, Chen Ruilin, Zheng Suqun, Wang Zhen, Zhou Linshui

Abstract excerpt

BACKGROUND: Oxidative stress is crucial in the immune response and airway inflammatory process associated with asthma. While the relationship between dietary antioxidants and asthma remains debated in observational studies, this study uses two-sample Mendelian randomization (MR) to explore a potential causal link. METHODS: We acquired six distinct categories of absolute circulating antioxidants and five different...

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Topics

Humans
Asthma
Mendelian Randomization Analysis
Antioxidants
Uric Acid
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genome-Wide Association Study

Ascorbic Acid

Vitamin A

Diet

beta Carotene

Lycopene

Vitamin E

Oxidative Stress

Source

Open in PubMed

Identifiers

PMID: 40908840
DOI: 10.1080/02770903.2025.2555297

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