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Integrating single-cell RNA sequencing and artificial intelligence for multitargeted drug design for combating resistance in liver cancer

2 Sept 2025

Abstract excerpt

Hepatocellular carcinoma (HCC) is an aggressive and heterogeneous liver cancer with restricted therapy selections and poor diagnosis. Although there have been great advances in genomics, the molecular mechanisms essential to HCC progression are not yet fully implicit, particularly at the single-cell stage. This research utilized single-cell RNA sequencing technology to evaluate transcriptional heterogeneity,...

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PMID: 40897921
DOI: 10.1038/s41698-025-00952-3

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