Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Irisin in Reproduction: Its Roles and Therapeutic Potential in Male and Female Fertility Disorders

27 Sept 2024

Abstract excerpt

The current study focused on identifying the potential of irisin in mammalian reproduction. The established role of irisin, a proteolytic product of FNDC5, in adipose tissue browning, energy metabolism, and thermogenesis suggests its role in reproductive health, often disturbed by metabolic imbalances. Various studies on mice demonstrated irisin's role in improving spermatogenesis, sperm count, and testosterone...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Fatty Acid Research and Health
Share to Stress Responses and Cortisol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39456155
DOI: 10.3390/biom14101222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Irisin in Reproduction: Its Roles and Therapeutic Potential in Male and Female Fertility DisordersPMID 39456155Read ↗

Irisin, Energy Homeostasis and Male ReproductionSemantic proximity Read ↗

Irisin as an emerging target in the regulation of reproductive functions in health and diseaseSemantic proximity Read ↗

Progress and Challenges in the Biology of FNDC5 and IrisinSemantic proximity Read ↗

Role and Functions of Irisin: A Perspective on Recent Developments and Neurodegenerative DiseasesSemantic proximity Read ↗

Browning of white fat: does irisin play a role in humans?Semantic proximity Read ↗

Irisin reduces the abnormal reproductive and metabolic phenotypes of PCOS by regulating the activity of brown adipose tissue in mice†.Semantic proximity Read ↗

Cleavage of FNDC5 and insights into its maturation process.Semantic proximity Read ↗

Fndc5 is translated from an upstream ATG start codon and cleaved to produce irisin myokine precursor protein in humans and miceSemantic proximity Read ↗

Unveiling the Role of Irisin as a Biomarker in Adolescent and Young Adult PCOS: A Metabolic and Hormonal Comparison of Hyperandrogenic and Normoandrogenic Phenotypes.Semantic proximity Read ↗

Insulin-like peptide 3 (INSL3) is a major regulator of female reproductive physiologySemantic proximity Read ↗

Myostatin: a multifunctional role in human female reproduction and fertility – a short reviewSemantic proximity Read ↗

Newly Identified Regulators of Ovarian Folliculogenesis and OvulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.