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Article

Genome-Wide Association Studies of Delay Discounting and Impulsive Personality Traits in Children From the Adolescent Behavior and Cognitive Development Study.

Genes, brain, and behavior - 1 Aug 2025

Deng Wei Q, Elsayed Mahmoud, Belisario Kyla L, Sanchez-Roige Sandra, Palmer Abraham A, MacKillop James

Abstract excerpt

Impulsivity, often operationalized as delay discounting (DD) and as impulsive personality traits via the UPPS-P scales, is a key transdiagnostic construct across psychiatric disorders. Recent genome-wide association studies (GWAS) have studied the genetic basis of impulsivity in adults, but it remains unclear how similar the genetic architecture of DD is in children. The present study conducted GWAS of DD and...

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PMID: 40847891
DOI: 10.1111/gbb.70033
PMCID: PMC12374252

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