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Article

The utility of next-generation sequencing in metastatic prostate cancer FNA biopsies.

Cancer cytopathology - 1 Sept 2025

Sirohi Deepika, Cornelia Ding Chien-Kuang, Stohr Bradley A, Balassanian Ronald, Vohra Poonam, Aggarwal Rahul, Chan Emily, Greenland Nancy Y

Abstract excerpt

BACKGROUND: Current American Society of Clinical Oncology guidelines state that patients with metastatic prostate cancer (MPC) should undergo germline and somatic DNA sequencing. The authors examined the utility of next-generation sequencing (NGS) on fine-needle aspiration (FNA) biopsies in which NGS was performed on cell block (CB) and/or smears. METHODS: A retrospective review was performed of cytology cases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40847760
DOI: 10.1002/cncy.70038
PMCID: PMC12374259

Genes

PTEN
TP53
BRCA2
CDK12
ERG
IDH1
INSM1
RB1
TMPRSS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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