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Article

RGMA gene polymorphisms as predictive biomarkers for early relapse in neuromyelitis optica spectrum disorders.

Neurobiology of disease - 15 Oct 2025

Yang Xiaoyi, Cui Lei, Jiao Jinsong, Zhang Yeqiong, Wang Renbin, Peng Dantao, Zhang Weihe

Abstract excerpt

OBJECTIVES: To explore the potential of RGMA gene polymorphisms as novel biomarkers for predicting disease activity in NMOSD. METHODS: We enrolled 117 NMOSD patients and 100 healthy controls. Single nucleotide polymorphism genotyping for the RGMA gene was performed using Sanger sequencing. Associations between RGMA gene polymorphisms and clinical and imaging characteristics, and immune cell activation were...

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Identifiers

PMID: 40845986
DOI: 10.1016/j.nbd.2025.107063

Genes

RGMA
AQP4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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