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Phenotypic and genomic features shaping the activity of a novel T4-like phage against clinical multidrug-resistant Klebsiella pneumoniae

2026-01-07

Abstract excerpt

<title>Abstract</title> <p> Background The use of bacteriophages holds a great promise in the treatment of multidrug resistant bacteria. The interaction between bacteriophages and multidrug-resistant <italic>Klebsiella pneumoniae</italic> is shaped by extensive capsular diversity, accessory genome variation and multilayered anti-phage defense systems, resulting in highly variable susceptibility profiles. Here...

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Literature Corpus work
74a5dce5-33f2-5b84-bc6e-ddc1e364806f
DOI
10.21203/rs.3.rs-8388477/v1
Open publication

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Phenotypic and genomic features shaping the activity of a novel T4-like phage against clinical multidrug-resistant Klebsiella pneumoniaeDOI 10.21203/rs.3.rs-8388477/v1
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