Article
Genomic and phenotypic characterization of Klebsiella pneumoniae phage KP Ø1: a novel lytic Slopekvirus targeting uropathogenic multidrug-resistant Klebsiella pneumoniae.
Scientific reports - 3 Sept 2026
Fadl Reham, Ismail Ghada, Elshafei Ahmed, Mokhtar Amira Mohamed, El Nabawy Omnia Mohamed, Gomaa Seadawy Mohamed, Baraka Mahmoud M, Sherif Basma
Abstract excerpt
The rise of multidrug-resistant (MDR) uropathogenic gram-negative bacteria (GNB) necessitates the development of alternative therapeutic strategies. This study aimed to isolate, phenotypically characterize, and perform whole-genome sequencing of the bacteriophage demonstrating the broadest host range against MDR uropathogens. Fifty MDR GNB isolates were screened for lytic phages. The most promising candidate,...
Read the complete abstract on PubMedTopics
- Klebsiella pneumoniae
- Bacteriophages
- Drug Resistance, Multiple, Bacterial
- Genome, Viral
- Phenotype