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Article

Readiness and leadership for the implementation of polygenic risk scores: Genetic healthcare providers' perspectives in the hereditary cancer context.

Journal of genetic counseling - 1 Aug 2025

Purvis Rebecca, Taylor Natalie, Young Mary-Anne, James Paul, Forrest Laura E

Abstract excerpt

Genetic healthcare providers and organizations must be made ready for potential future clinical implementation of polygenic risk scores (PRS) for hereditary breast and ovarian (HBOC) cancer risk assessment. Understanding the multi-level factors that contribute to readiness for change will assist leaders with strategic planning and selection of facilitative implementation strategies, ultimately reducing resource...

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PMID: 40692272
DOI: 10.1002/jgc4.70084
PMCID: PMC12280534

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