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Characterization of Highly Ferulate-Tolerant Acinetobacter baylyi ADP1 Isolates by a Rapid Reverse Engineering Method.

Applied and environmental microbiology - 25 Jan 2022

Luo Jin, McIntyre Emily A, Bedore Stacy R, Santala Ville, Neidle Ellen L, Santala Suvi

Abstract excerpt

Adaptive laboratory evolution (ALE) is a powerful approach for improving phenotypes of microbial hosts. Evolved strains typically contain numerous mutations that can be revealed by whole-genome sequencing. However, determining the contribution of specific mutations to new phenotypes is typically challenging and laborious. This task is complicated by factors such as the mutation type, the genomic context, and the...

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PMID: 34788063
DOI: 10.1128/AEM.01780-21
PMCID: PMC8788691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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