Article
Genetic Variants Affect Distinct Metabolic Pathways in Pediatric Multisystem Inflammatory Syndrome and Severe COVID-19.
Journal of medical virology - 1 Aug 2025
Urbanski Alysson Henrique, Freitas Flávia Cristina de Paula, Gomes Tiago Minuzzi Freire da Fontoura, Schemberger Michelle Orane, Reis Bárbara Carvalho Santos Dos, Carvalho Flavia Amêndola Anísio de, Faccion Roberta Soares, Machado Lucas de Almeida, Santos Deborah Antunes Dos, Cunha Daniela Prado, Salú Margarida Dos Santos, Moore Daniella Campelo Batalha Cox, Presibella Mayra Marinho, Noguchi Juliana Fontes, Borges Henrique Lira, Tomiura Lais Kimie, Silva de Castro Luiza, Santos Letícia Graziela Costa, Silva Esdras Matheus Gomes da, Parreira Vinícius Da Silva Coutinho, Morello Luis Gustavo, Marchini Fabricio Klerynton, Tizzot Maria Regina, Ribas Mauricio Marcondes, Pascolat Gilberto, Ribas Carmen Australia Paredes Marcondes, Vicente Fábio Fernandes da Rocha, Paschoal Alexandre Rossi, Cat Rubens, Carvalho Benilton de Sá, Carvalho de Oliveira Jaqueline, Oliveira Marcus F, Coutinho Luiz Lehmann, Nasr Acácia Maria Lourenço Francisco, Riediger Irina Nastassja, Nardin Jeanine Marie, Mikami Liya Regina, Guimarães Ana Carolina Ramos, Savio de Araujo-Souza Patricia, Prata-Barbosa Arnaldo, Vasconcelos Zilton Farias Meira de, Faoro Helisson, Geremias Dos Santos Hellen, Passetti Fabio
Abstract excerpt
The coronavirus disease 2019 (COVID-19) pandemic has triggered a global health crisis, with over 700 million confirmed cases and at least 7 million deaths reported by early 2024. Children are less vulnerable to severe SARS-CoV-2 infection than adults and typically experience milder respiratory symptoms. However, a rare but significant complication, known as multisystem inflammatory syndrome in children (MIS-C),...
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