Article
Host genetic susceptibility underlying SARS-CoV-2-associated Multisystem Inflammatory Syndrome in Brazilian Children.
Molecular medicine (Cambridge, Mass.) - 12 Dec 2022
Santos-Rebouças Cíntia Barros, Piergiorge Rafael Mina, Dos Santos Ferreira Cristina, Seixas Zeitel Raquel de, Gerber Alexandra Lehmkuhl, Rodrigues Marta Cristine Felix, Guimarães Ana Paula de Campos, Silva Rodrigo Moulin, Fonseca Adriana Rodrigues, Souza Rangel Celso, de Souza Ana Tereza Antunes Monteiro, Rossi Átila Duque, Porto Luís Cristóvão de Moraes Sobrino, Cardoso Cynthia Chester, de Vasconcelos Ana Tereza Ribeiro
Abstract excerpt
BACKGROUND: Multisystem Inflammatory Syndrome in Children (MIS-C) is a life-threatening complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which manifests as a hyper inflammatory process with multiorgan involvement in predominantly healthy children in the weeks following mild or asymptomatic coronavirus disease 2019 (COVID-19). However, host monogenic predisposing factors to...
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