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Article

Genetic insights into MIS-C Post-COVID-19 in Kuwaiti children: investigating monogenic factors.

Frontiers in cellular and infection microbiology - 1 Jan 2024

Dashti Mohammed, AlKandari Hessa, Malik Md Zubbair, Nizam Rasheeba, John Sumi Elsa, Jacob Sindhu, Channanath Arshad, Othman Fouzeyah, Al-Sayed Safa, Al-Hindi Osama, Al-Mutari Mona, Thanaraj Thangavel Alphonse, Al-Mulla Fahd

Abstract excerpt

Background: Multisystem inflammatory syndrome in children (MIS-C) is a severe complication arising from SARS-CoV-2 infection, with indications that rare inborn errors of immunity may play a role in its pathogenesis. Recent studies suggest that genetic predispositions, particularly monogenic forms, could significantly influence the immune responses to SARS-CoV-2 in MIS-C. Methods: We analysed 24 children under 12...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39844836
DOI: 10.3389/fcimb.2024.1444216
PMCID: PMC11750811

Genes

DDX60
TMEM154

Provenance

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