Saposins: structure, function, distribution, and molecular genetics.

Article

Saposins: structure, function, distribution, and molecular genetics.

Journal of lipid research - 1 Sept 1992

Kishimoto Y, Hiraiwa M, O'Brien J S

Abstract excerpt

Saposins A, B, C, and D are small heat-stable glycoproteins derived from a common precursor protein, prosaposin. These mature saposins, as well as prosaposin, activate several lysosomal hydrolases involved in the metabolism of various sphingolipids. All four saposins are structurally similar to o...

Topics

Animals
Glycoproteins
Humans
Lysosomal Storage Diseases
Mutation
Saposins
Sphingolipid Activator Proteins
Tissue Distribution

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