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Article

Protective association of the ELMO1 rs741301 variant against diabetes mellitus and diabetic nephropathy: a systematic meta-analysis of case-control studies.

Annals of human biology - 1 Dec 2026

Thomas Sheena Mariam, Anilkumar Anu Shibi, Veerabathiran Ramakrishnan

Abstract excerpt

CONTEXT: Diabetes mellitus (DM), an endocrine disorder, is characterised by persistently elevated blood glucose levels due to inadequate insulin production. Diabetic nephropathy (DN), is a critical complication associated with DM, often leading to end-stage renal failure and increased mortality. OBJECTIVE: This meta-analysis aimed to evaluate the association between the ELMO1 rs741301 polymorphism and...

Read the complete abstract on PubMed

Topics

Humans
Diabetic Nephropathies
Adaptor Proteins, Signal Transducing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Case-Control Studies

Polymorphism, Single Nucleotide

Genetic Predisposition to Disease

Diabetes Mellitus

Source

Identifiers

PMID: 42684113
DOI: 10.1080/03014460.2026.2723114

Genes

ELMO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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Protective association of the ELMO1 rs741301 variant against diabetes mellitus and diabetic nephropathy: a systematic meta-analysis of case-control studies.PMID 42684113Read ↗

Association between ELMO1 gene polymorphisms and diabetic kidney disease: A systematic review and meta-analysis.Semantic proximity Read ↗

Association between ELMO1 gene polymorphisms and diabetic nephropathy in an Iranian populationSemantic proximity Read ↗

Association of the ELMO1 gene (snp rs1345365) with development of type 2 diabetes mellitus in the Mexican mestizo population.Semantic proximity Read ↗

Association of ELMO1 gene polymorphism and diabetic nephropathy among Egyptian patients with type 2 diabetes mellitus.Semantic proximity Read ↗

Association of single nucleotide polymorphism (rs741301) of the ELMO1 gene with diabetic kidney disease in Polish patients with type 2 diabetes: a pilot study.Semantic proximity Read ↗

Association of Genetic Variants of ELMO1 Gene With Diabetic Nephropathy in the North Indian PopulationSemantic proximity Read ↗

Association of ELMO1 gene polymorphisms with diabetic nephropathy in Chinese population.Semantic proximity Read ↗

ELMO1 variants and susceptibility to diabetic nephropathy in American Indians.Semantic proximity Read ↗

Association of rs11643718 SLC12A3 and rs741301 ELMO1 Variants with Diabetic Nephropathy in South Indian Population.Semantic proximity Read ↗

Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy.Semantic proximity Read ↗

Variations in CCR5, but not HFE, ELMO1, or SLC12A3, are associated with susceptibility to kidney disease in north Indian individuals with type 2 diabetes.Semantic proximity Read ↗

Associations of MALAT1 rs619586/rs3200401 and ANRIL rs10965215/rs10738605 polymorphisms with type 2 diabetes and diabetic nephropathy risk in an Egyptian population.Semantic proximity Read ↗

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