Article
Could the Polymorphisms of DOCK4 (rs147636134), SYNGAP1 (rs199759879), and FOXP1 (rs767001715) be the Primary Risk Factors for Bipolar Disorder and Autism Spectrum Disorder?
Developmental neurobiology - 1 Oct 2025
Çiftçi Elvan, Sağlam Nimet, Gözler Tayfun, Yüksel İpek, Kilit Neriman, Bozkurt İlknur, Konuk Muhsin, Ulucan Korkut, Tarhan Nevzat
Abstract excerpt
Autism spectrum disorder (ASD) and bipolar disorder (BD) are psychiatric diseases that may overlap in common neurodevelopmental and genetic basis. Forkhead Box P1 (FOXP1), Synaptic Ras GTPase-activating protein 1 (SYNGAP1), and Dedicator of Cytokinesis 4 (DOCK4) genes are critical for synaptic plasticity, neuronal communication, and brain development. This study aims to investigate the association of FOXP1...
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