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Article

SNP-PCR genotyping links alterations in the GABAA receptor (GABRG3: rs208129) and RELN (rs73670) genes to autism spectrum disorder among peadiatric Iraqi Arabs.

Molecular biology reports - 1 Jul 2022

Ali Zainab A, Yasseen Akeel A, McAllister Katherine A, Al-Dujailli Arafat, Al-Karaqully Ahmed J, Jumaah Alaa S

Abstract excerpt

INTRODUCTION: Autism spectrum disorder (ASD) is an increasing concern among the Iraqi Arab population. The genetic alterations that cause ASD are likely to converge at the synapse. This study investigated polymorphisms in the GABAA receptor subunit (GABRG3) and the RELN gene as putative biomarkers of ASD in a pediatric population in Iraq. METHODS: The case control study included 60 patients with a clinical...

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Identifiers

PMID: 35403940
DOI: 10.1007/s11033-022-07388-z
PMCID: PMC9270290

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