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CRISPR/Cas technologies in pancreatic cancer research and therapeutics: recent advances and future outlook

11 Aug 2025

Abstract excerpt

Pancreatic cancer is marked by a poor prognosis and an exceptionally high mortality rate, with its aggressive nature contributing to its classification as a highly malignant disease. For effective therapeutic strategies, the development of sophisticated and regulated DNA manipulation methods is essential. Originally part of the prokaryotic immune system, CRISPR/Cas has emerged as a pivotal genome-editing tool...

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PMID: 40789802
DOI: 10.1007/s12672-025-03383-5

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