Article

Efficacy of CRISPR-Cas9 Gene Editing for Targeting KRAS Mutations in Pancreatic Cancer: A systematic review

2024-10-21

Abstract excerpt

<title>Abstract</title> <p>Background Pancreatic cancer is one of the main causes of cancer-related deaths, especially pancreatic ductal adenocarcinoma and it’s characterized by a poor prognosis. The KRAS gene mutation is prevalent in about 85% of pancreatic cancer cases which is a significant factor in the pathogenesis and development of pancreatic cancer, impacting cellular tumor growth, survival, and metastas...

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Literature Corpus work: 3824aa42-e147-5502-a363-edb5142270e4
DOI: 10.21203/rs.3.rs-5001819/v1

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