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Article

Particle Shape Modulates the Function of Adoptive Macrophage Transfers.

Advanced healthcare materials - 1 Dec 2025

Kwan Matthew M C, Day Nicole B, Konigsberg Iain R, Thoresen Evan, Harrell Abigail G, Busch Celeste E, Davidson Elizabeth J, Yang Ivana V, Shields C Wyatt

Abstract excerpt

Adoptive cell transfers (ACTs) constitute an emerging platform for improving the systemic delivery of nano- and microparticle systems. Macrophages (Mφ) are an attractive cell type for particle-carrying ACTs because their attachment, phagocytosis, and chemotaxis can improve pharmacokinetics and reduce off-target effects. However, little is known about how macrophage transport and function change when carrying...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40776442
DOI: 10.1002/adhm.202501348
PMCID: PMC12431639

Genes

F10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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