Personalized colorectal cancer risk assessment through explainable AI and Gut microbiome profiling

Abstract excerpt

The clinical adenoma – carcinoma progression represents a well-established framework for understanding colorectal cancer (CRC) development, although the molecular mechanisms underlying this transition remain only partially understood. Increasing evidence suggests the gut microbiome (GM) as a key modulator of colorectal carcinogenesis, positioning microbial profiling as a promising avenue for noninvasive risk...

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