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Gut microbiome differences and disease risk in colorectal cancer relatives and healthy individuals

24 Mar 2025

Abstract excerpt

Given the heightened focus on high-risk populations, this study aimed to provide insights into early susceptibility and preventive strategies for colorectal cancer (CRC) by focusing on high-risk populations. In this research, fecal samples from 1,647 individuals across three discovery cohorts and nine external validation cohorts were sequenced using whole-genome metagenomic sequencing. A prediction model based on...

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PMID: 40196042
DOI: 10.3389/fcimb.2025.1573216

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