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Leveraging sequence-based faecal microbial community survey data to identify a composite biomarker for colorectal cancer

24 Mar 2017

Abstract excerpt

OBJECTIVE: Colorectal cancer (CRC) is the second leading cause of cancer-associated mortality in the USA. The faecal microbiome may provide non-invasive biomarkers of CRC and indicate transition in the adenoma-carcinoma sequence. Re-analysing raw sequence and metadata from several studies uniformly, we sought to identify a composite and generalisable microbial marker for CRC. DESIGN: Raw 16S rRNA gene sequence...

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Share to Bacterial Identification and Susceptibility Testing
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PMID: 28341746
DOI: 10.1136/gutjnl-2016-313189

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