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Article

Molecular Characterization of Pancreatic Simple Mucinous Cysts With GNAS Mutation: A Case Report and Literature Review.

Pancreas - 1 Jan 2026

Mizukami Shoichiro, Imai Koji, Takahashi Hiroyuki, Shimada Shingo, Tamamura Nobue, Mori Miyuki, Nishikawa Koji, Ono Yusuke, Tanino Mishie, Mizukami Yusuke, Yokoo Hideki

Abstract excerpt

OBJECTIVES: Pancreatic simple mucinous cysts (SMCs) are characterized by cystic lesions >1 cm in size, lacking ovarian-type stroma and lined by a single layer of bland epithelium. Although SMCs are typically considered benign, sporadic cases with KRAS mutations suggest its potential inclusion within the spectrum of low-grade mucinous neoplasms. This study reported a case of pancreatic SMC with co-occurring KRAS...

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Share to Chromogranins
Share to GNAS gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to KRAS gene

Share to GTP-Binding Protein alpha Subunits

Share to GTP-Binding Protein alpha Subunits, Gs

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Share to Pancreatic Neoplasms

Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 40743430
DOI: 10.1097/MPA.0000000000002535

Genes

GNAS
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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