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Article

Association of KIM-1 (HAVCR1) Expression with the Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma

29 Jul 2025

Abstract excerpt

Introduction: Kidney injury molecule 1 (KIM-1) is a cell-surface glycoprotein expressed in the proximal tubules and encoded by the hepatitis A virus cellular receptor 1 (HAVCR1) gene. It is also expressed in renal cell carcinoma (RCC). Objective: This study examined the immune landscape of clear cell RCC in association with HAVCR1 expression. Methods: Next-generation sequencing (NGS) data from ccRCC tumor samples...

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PMID: 40735979
DOI: 10.2174/0115665232402424250721114133

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