Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of organic anion transporting polypeptides in hepatocellular carcinoma

15 Jul 2025

Abstract excerpt

Introduction Hepatocellular carcinoma (HCC) is the most common primary liver malignancy, predominantly occurring in patients with underlying chronic liver disease, including cirrhosis. Organic anion transporter polypeptides (OATPs), encoded by SLCO genes, are one of the most important SLC subfamilies involved in the cellular uptake of drugs and endobiotic. OATP1B1 (SLCO1B1 gene), OATP1B3 (SLCO1B3 gene), and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Enzymes and Metabolism
Share to Drug Transport and Resistance Mechanisms
Share to Trace Elements in Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40734706
DOI: 10.3389/fgene.2025.1550723

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of organic anion transporting polypeptides in hepatocellular carcinomaPMID 40734706Read ↗

The Expression and Function of Organic Anion Transporting Polypeptides in Normal Tissues and in CancerSemantic proximity Read ↗

Organic anion-transporting polypeptides: a novel approach for cancer therapySemantic proximity Read ↗

Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy.Semantic proximity Read ↗

A cancer-specific variant of the SLCO1B3 gene encodes a novel human organic anion transporting polypeptide 1B3 (OATP1B3) localized mainly in the cytoplasm of colon and pancreatic cancer cells.Semantic proximity Read ↗

[Advances in the study of organic anion transporting polypeptide 1B3].Semantic proximity Read ↗

Expression of OATP Family Members in Hormone-Related Cancers: Potential Markers of ProgressionSemantic proximity Read ↗

Bioinformatics and machine learning driven key genes screening for hepatocellular carcinomaSemantic proximity Read ↗

Clinical and Genetic Determinants of Hepatocellular Carcinoma in a Turkish Cohort: Impact of SLCO1B1 and SLCO1B3 Germline Variations and Demographic Risk Factors.Semantic proximity Read ↗

Identification of a new organic anion transporting polypeptide 1B3 mRNA isoform primarily expressed in human cancerous tissues and cellsSemantic proximity Read ↗

Loss of alanine-glyoxylate and serine-pyruvate aminotransferase expression accelerated the progression of hepatocellular carcinoma and predicted poor prognosis.Semantic proximity Read ↗

Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcomeSemantic proximity Read ↗

Identification of ABCC5 Among ATP-Binding Cassette Transporter Family as a New Biomarker for Hepatocellular Carcinoma Based on Bioinformatics AnalysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.