Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome

1 Nov 2008

Abstract excerpt

BACKGROUND AND AIMS: OATP1B3 is an organic anion transporting polypeptide (OATP) that functions as a multispecific transporter in the normal liver. We examined the expression and clinical significance of OATP1B3 in colon cancers in tissue microarrays. METHODS: Immunohistochemistry was used to assess OATP1B3 protein expression in paraffinized colon tumor tissue microarrays. OATP1B3 immunostaining was evaluated by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Enzymes and Metabolism
Share to Drug Transport and Resistance Mechanisms
Share to Gastroesophageal reflux and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21677819
DOI: 10.2147/ceg.s3743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcomePMID 21677819Read ↗

A cancer-specific variant of the SLCO1B3 gene encodes a novel human organic anion transporting polypeptide 1B3 (OATP1B3) localized mainly in the cytoplasm of colon and pancreatic cancer cells.Semantic proximity Read ↗

Roles of organic anion transporting polypeptides in hepatocellular carcinomaSemantic proximity Read ↗

Modulation of OATP1B-Type Transporter Function Alters Cellular Uptake and Disposition of Platinum ChemotherapeuticsSemantic proximity Read ↗

Expression of OATP Family Members in Hormone-Related Cancers: Potential Markers of ProgressionSemantic proximity Read ↗

[Advances in the study of organic anion transporting polypeptide 1B3].Semantic proximity Read ↗

Identification of a new organic anion transporting polypeptide 1B3 mRNA isoform primarily expressed in human cancerous tissues and cellsSemantic proximity Read ↗

The role of OATP1B1 and OATP1B3 transporter polymorphisms in drug disposition and response to anticancer drugs: a review of the recent literatureSemantic proximity Read ↗

The Expression and Function of Organic Anion Transporting Polypeptides in Normal Tissues and in CancerSemantic proximity Read ↗

miR-183 functions as an oncogene by targeting ABCA1 in colon cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.