Article
The origin and functions of multiple human glucocorticoid receptor isoforms.
Annals of the New York Academy of Sciences - 1 Jun 2004
Lu Nick Z, Cidlowski John A
Abstract excerpt
Glucocorticoid hormones are necessary for life and are essential in all aspects of human health and disease. The actions of glucocorticoids are mediated by the glucocorticoid receptor (GR), which binds glucocorticoid hormones and regulates gene expression, cell signaling, and homeostasis. Decades of research have focused on the mechanisms of action of one isoform of GR, GRa. However, in recent years, increasing...
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