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Article

Causal Relationships Between Gastroesophageal Reflux Disease and Myocardial Infarction: Insights From Univariable and Multivariable Mendelian Randomization Analyses.

Annals of human genetics - 1 Jan 2026

Zheng Xiaoya, Hu Teng, Fang Tianxiang, Su Pengpeng, Wang Yingsong, Huangfu Ning

Abstract excerpt

BACKGROUND: Observational studies have indicated that gastroesophageal reflux disease (GERD) is connected to myocardial infarction (MI). Nonetheless, the question of causality in these relationships remains unresolved, given the potential influence of confounding variables. The aim is to study the causal link of GERD with MI and determine whether MI factors have any mediation effects in the causative chain....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40719212
DOI: 10.1111/ahg.70012
PMCID: PMC12698889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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