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Article

Causal analysis of gastroesophageal reflux disease and esophageal cancer

15 Mar 2024

Abstract excerpt

Patients with gastroesophageal reflux disease (GERD) are more likely to develop esophageal cancer (EC). However, a causal relationship between the 2 has been difficult to determine. Therefore, this study aimed to evaluate the impact of GERD on EC using the Mendelian randomization (MR) method. The causal association between GERD and EC was analyzed based on 2 publicly available genetic summary datasets for the...

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PMID: 38489737
DOI: 10.1097/md.0000000000037433

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