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Article

Association of the CC chemokine receptor 5 (CCR5) polymorphisms with preeclampsia in Turkish women.

Archives of gynecology and obstetrics - 1 Jul 2012

Gurdol Figen, Yurdum Leman M, Ozturk Ummuhan, Isbilen Elif, Cakmakoglu Bedia

Abstract excerpt

AIM: Endothelial dysfunction and inflammation are involved in the pathogenesis of preeclampsia. The CC chemokine receptor 5 (CCR5) modulates inflammation secondary to endothelial dysfunction and related vascular disorders, by initiating chemotaxis. In this study, we examined the frequency of two polymorphisms, the CCR5D32 deletion and the CCR5-59029 A/G promoter point mutation in women with preeclampsia. METHODS:...

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Identifiers

PMID: 22314435
DOI: 10.1007/s00404-012-2244-3

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CCR5

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