Article
Relation of FTO gene variants to fetal growth trajectories: Findings from the Southampton Women's survey.
Placenta - 1 Feb 2016
Barton S J, Mosquera M, Cleal J K, Fuller A S, Crozier S R, Cooper C, Inskip H M, Holloway J W, Lewis R M, Godfrey K M
Abstract excerpt
INTRODUCTION: Placental function is an important determinant of fetal growth, and fetal growth influences obesity risk in childhood and adult life. Here we investigated how FTO and MC4R gene variants linked with obesity relate to patterns of fetal growth and to placental FTO expression. METHODS: Southampton Women's Survey children (n = 1990) with measurements of fetal growth from 11 to 34 weeks gestation were...
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