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Article

Lifestyle, genetic susceptibility, and risk of diverticular disease: a prospective cohort study.

International journal of surgery (London, England) - 1 Dec 2025

Guo Chuan-Guo, Wang Jiaxin, Liu Yufan, Yu Wen, Shao Cuicui, Zhang Feifei

Abstract excerpt

BACKGROUND: Emerging evidence indicates that diverticular disease is attributed to both environmental and genetic factors. The impact of modifiable lifestyle factors on diverticular disease has not been fully elucidated, particularly regarding the role of genetic predisposition. MATERIALS AND METHODS: We performed a prospective cohort study using data from the UK Biobank, which included 472 612 participants. The...

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PMID: 40694019
DOI: 10.1097/JS9.0000000000003087
PMCID: PMC12695229

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