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Article

Sedentary lifestyle, physical activity, and gastrointestinal diseases: evidence from mendelian randomization analysis.

EBioMedicine - 1 May 2024

Chen Jie, Ruan Xixian, Fu Tian, Lu Shiyuan, Gill Dipender, He Zixuan, Burgess Stephen, Giovannucci Edward L, Larsson Susanna C, Deng Minzi, Yuan Shuai, Li Xue

Abstract excerpt

BACKGROUND: The causal associations of physical activity and sedentary behavior with the risk of gastrointestinal disease are unclear. We performed a Mendelian randomization analysis to examine these associations. METHODS: Genetic instruments associated with leisure screen time (LST, an indicator of a sedentary lifestyle) and moderate-to-vigorous intensity physical activity (MVPA) at the genome-wide significance...

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Identifiers

PMID: 38583262
DOI: 10.1016/j.ebiom.2024.105110
PMCID: PMC11004085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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