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Article

Air pollution exposure modes, smoking and genetic risk with chronic respiratory diseases: a prospective study.

NPJ primary care respiratory medicine - 5 Dec 2025

Wang Ting, Lyu Linfang, Yuan Ru, Lei Lei, Meng Fanqing, Zhu Meng, Duan Weiwei

Abstract excerpt

Previous studies often focused on single pollutant source, failing to replicate real-world exposure scenarios for chronic respiratory disease (CRD) risk. We aimed to explore the mixed exposure patterns of CRD risk factors and investigate interactions with smoking and genetic risk. We identified air pollution exposure modes using latent class analysis (LCA) in the UK Biobank. Cox model assessed associations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41350531
DOI: 10.1038/s41533-025-00469-z
PMCID: PMC12800334

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