Article

Circulating MicroRNA Signatures in Severe Alopecia Areata: Diagnostic Discrimination, Pathway Analysis, and Therapeutic Implications

2025-07-25

Abstract excerpt

<h4>Introduction: </h4> Alopecia areata (AA) is an autoimmune disorder characterized by non-scarring hair loss due to immune dysregulation. Despite advances, its precise molecular mechanisms remain unclear. This study investigates plasma miRNA expression profiles in patients with AA to identify biological pathways influenced by miRNAs and potential therapeutic targets. <h4>Methods:</h4> Fifty patients with AA were...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 657db132-6655-5d9e-b90b-5a00dc979e2c
DOI: 10.20944/preprints202505.0857.v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Circulating MicroRNA Signatures in Severe Alopecia Areata: Diagnostic Discrimination, Pathway Analysis, and Therapeutic ImplicationsDOI 10.20944/preprints202505.0857.v2Read

Construction of regulatory network for alopecia areata progression and identification of immune monitoring genes based on multiple machine-learning algorithmsSemantic proximity Read

Identification of differentially expressed miRNAs in alopecia areata that target immune-regulatory pathwaysSemantic proximity Read

Prediction of the Risk of Alopecia Areata Progressing to Alopecia Totalis and Alopecia Universalis: Biomarker Development with Bioinformatics Analysis and Machine LearningSemantic proximity Read

Molecular signatures define alopecia areata subtypes and transcriptional biomarkersSemantic proximity Read

Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areataSemantic proximity Read

Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory DiseasesSemantic proximity Read

MiR‐200c‐3p as a novel genetic marker and therapeutic tool for alopecia areataSemantic proximity Read

Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review.Semantic proximity Read

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity.Semantic proximity Read

miRNA expression profiles of the perilesional skin of atopic dermatitis and psoriasis patients are highly similarSemantic proximity Read

Deciphering the Complex Immunopathogenesis of Alopecia AreataSemantic proximity Read

Proteomic Predictors of Baricitinib Response in Severe Alopecia Areata: CCL11 Flags a Refractory PhenotypeSemantic proximity Read