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Multomic analysis reveals the potential of LAG3 as a prognostic and immune biomarker and its validation in osteosarcoma

11 Jul 2025

Abstract excerpt

Lymphocyte activation gene 3 (LAG3) is a member of the immunoglobulin superfamily and has been implicated in the development, growth, and progression of several cancers. However, the biological role of LAG3 has not been investigated in pan-cancer datasets. We sought to perform a comprehensive bioinformatics analysis of pan-cancer datasets to determine the relationship of LAG3 with patient survival prognosis,...

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Cancer Immunotherapy and Biomarkers
Cancer-related molecular mechanisms research
RNA modifications and cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40646089
DOI: 10.1038/s41598-025-10290-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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