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Modulation of mitochondrial quality control through autophagic pathway in familial Alzheimer's disease

7 Jul 2025

Abstract excerpt

Autophagy is a highly conserved cellular catabolic process recognized as an essential pathway for the maintenance of cellular homeostasis. Growing evidence implicates autophagic dysfunction in the pathogenesis of several neurodegenerative disorders, including Alzheimer's disease (AD), thus its modulation might represent an interesting therapeutic tool. Searching for a compound that stimulates autophagic pathway,...

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PMID: 40633621
DOI: 10.1016/j.bbamcr.2025.120019

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