Article
Idiopathic Pulmonary Fibrosis Is Associated With Type 1 Diabetes: A Two-Sample Mendelian Randomization Study.
The journal of gene medicine - 1 Jan 2025
Chen Leyan, Hou Tianzhichao, Ge Feifan, Jiang Huachi, Liu Feng, Tian Jingyan, Zheng Mingfeng
Abstract excerpt
BACKGROUND: The pathogenesis of idiopathic pulmonary fibrosis (IPF) remains unclear; previous studies revealed the underlying connection between IPF and diabetes, but there is no consensual opinion. This study is aimed at examining the association between Type 1 diabetes (T1D) and IPF using Mendelian randomization (MR). METHOD: In our two-sample MR study, we selected single nucleotide polymorphisms (SNPs) that...
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