Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role and therapeutic potential of glucose metabolism in multidrug resistance of cancer

19 Jun 2025

Abstract excerpt

Cancer represents a serious threat to human health and life. Despite recent advances in the cancer therapy that significantly extend patient survival, many individuals still undergo drug resistance, even to multiple chemotherapeutic drugs, known as multidrug resistance (MDR). MDR causes the treatment failure and promotes the risk of tumor recurrence and metastasis, which has been a critical clinical challenge....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Drug Transport and Resistance Mechanisms
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40612109
DOI: 10.3389/fcell.2025.1584630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role and therapeutic potential of glucose metabolism in multidrug resistance of cancerPMID 40612109Read ↗

The roles of glucose metabolic reprogramming in chemo- and radio-resistanceSemantic proximity Read ↗

Reprogramming of glucose metabolism: The hallmark of malignant transformation and target for advanced diagnostics and treatmentsSemantic proximity Read ↗

Glucose addiction in cancer therapy: advances and drawbacksSemantic proximity Read ↗

Moonlighting functions of glucose metabolic enzymes and metabolites in cancerSemantic proximity Read ↗

Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potentialSemantic proximity Read ↗

[Therapeutic strategies targeting cancer--specific metabolism].Semantic proximity Read ↗

The Emerging Roles of the Metabolic Regulator G6PD in Human CancersSemantic proximity Read ↗

Glucose transporters: expression, regulation and cancerSemantic proximity Read ↗

Cancer Metabolism: Phenotype, Signaling and Therapeutic Targets.Semantic proximity Read ↗

Role of Glucose Metabolism Reprogramming in the Pathogenesis of CholangiocarcinomaSemantic proximity Read ↗

Warburg effect and lactylation in cancer: mechanisms for chemoresistanceSemantic proximity Read ↗

Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.