Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ETV1 genetic polymorphisms as a candidate prognosis biomarker of Gastrointestinal stromal tumor.

Cancer chemotherapy and pharmacology - 2 Jul 2025

Zhuang Wei, Jo Minju, Qiu Haibo, Lin Wanlong, Huang Min, Wang Xueding

Abstract excerpt

PURPOSE: While imatinib is effective for treating Gastrointestinal Stromal Tumors (GISTs), significant variability in patient outcomes exists, highlighting the need for reliable prognostic biomarkers. ETV1, a key transcription factor involved in GIST progression, is implicated in disease biology, but the role of ETV1-related single nucleotide polymorphisms (SNPs) in predicting prognosis remains unclear. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Gastrointestinal Neoplasms

Share to Gastrointestinal Stromal Tumors

Share to Imatinib Mesylate

Share to MicroRNAs

Share to Progression-Free Survival

Source

Identifiers

PMID: 40601091
DOI: 10.1007/s00280-025-04789-2

Genes

ETV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ETV1 genetic polymorphisms as a candidate prognosis biomarker of Gastrointestinal stromal tumor.PMID 40601091Read ↗

Gene Expression Network Analysis of ETV1 Reveals KCTD10 as a Novel Prognostic Biomarker in Gastrointestinal Stromal TumorSemantic proximity Read ↗

Genetic polymorphisms as predictive biomarker of survival in patients with gastrointestinal stromal tumors treated with sunitinib.Semantic proximity Read ↗

Pharmacogenetics in the treatment of gastrointestinal stromal tumors - an updated review.Semantic proximity Read ↗

Low ETV1 mRNA expression is associated with recurrence in gastrointestinal stromal tumors.Semantic proximity Read ↗

KIT/PDGFRA Variant Allele Frequency as Prognostic Factor in Gastrointestinal Stromal Tumors (GISTs): Results From a Multi-Institutional Cohort Study.Semantic proximity Read ↗

MAPKAP kinase 2 overexpression influences prognosis in gastrointestinal stromal tumors and associates with copy number variations on chromosome 1 and expression of p38 MAP kinase and ETV1.Semantic proximity Read ↗

ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours.Semantic proximity Read ↗

An exploratory association of polymorphisms in angiogenesis-related genes with susceptibility, clinical response and toxicity in gastrointestinal stromal tumors receiving sunitinib after imatinib failure.Semantic proximity Read ↗

Identification of D842V mutation in gastrointestinal stromal tumors based on CT radiomics: a multi-center study.Semantic proximity Read ↗

ETV4 collaborates with Wnt/β-catenin signaling to alter cell cycle activity and promote tumor aggressiveness in gastrointestinal stromal tumorSemantic proximity Read ↗

Genetic polymorphisms in angiogenesis-related genes are associated with worse progression-free survival of patients with advanced gastrointestinal stromal tumours treated with imatinib.Semantic proximity Read ↗

Novel Clinically Relevant Genes in Gastrointestinal Stromal Tumors Identified by Exome SequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.