Article
Identification of D842V mutation in gastrointestinal stromal tumors based on CT radiomics: a multi-center study.
Cancer imaging : the official publication of the International Cancer Imaging Society - 20 Dec 2024
Xie Zhenhui, Zhang Qingwei, Zhang Ranying, Zhao Yuxuan, Zhang Wang, Song Yang, Yu Dexin, Lin Jiang, Li Xiaobo, Suo Shiteng, Zhou Yan
Abstract excerpt
BACKGROUND: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Recent advent of tyrosine kinase inhibitors (TKIs) has significantly improved the prognosis of GIST patients. However, responses to TKI therapy can vary depending on the specific gene mutation. D842V, which is the most common mutation in platelet-derived growth factor receptor alpha exon 18,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.