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A single-cell transcriptomic atlas of human lens epithelium: identification and functional insights into lens stem/progenitor cells

1 Jul 2025

Abstract excerpt

BACKGROUND: The existence of stem/progenitor cells in the lens epithelium has been demonstrated, but their identification remains challenging. Accurate identification requires advanced technologies and a comprehensive understanding of lens epithelial cell (LEC) subtypes, presenting a significant challenge in age-related cataract research. METHODS: Eight pairs of human donor lens epithelium samples were collected...

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PMID: 40598599
DOI: 10.1186/s13287-025-04436-w

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