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Article

Assessment of the causal influence of herpesvirus infections on the risk of depression phenotypes: A Mendelian randomization study.

Journal of psychosomatic research - 1 Aug 2025

Li Yi, Liu Zhenqiu, Fan Hong, Tao Sijie, Wang Haili, Zhang Xin, Wu Sheng, Xu Yiyun, Wang Tianye, Yang Ying, Zhang Tiejun

Abstract excerpt

OBJECTIVE: Previous findings of associations between herpesvirus infections and depression were mixed and did not implicate causality. This study used two-sample Mendelian randomization (MR) to clarify the causal impact of four symptomatic herpesvirus infections (shingles, chicken pox, cold sores, and mononucleosis) on three depression phenotypes, including depressive symptoms (DS), number of episodes with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40592101
DOI: 10.1016/j.jpsychores.2025.112194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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