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Transcriptomic Patterns in Adult and Pediatric Patients with IgA Nephropathy or IgA Vasculitis with Nephropathy

1 Jul 2025

Abstract excerpt

Key Points Inflammation and immune response pathways were enriched in IgA nephropathy/IgA vasculitis with nephropathy compared with living donors. The transcriptomic profile differed significantly between adults and children with the disease. Background Disease manifestations and progression of IgA nephropathy vary widely between individuals, particularly between children and adults. To further understand these...

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PMID: 40591410
DOI: 10.1681/asn.0000000787

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