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Article

Polygenic Risk for Substance Use Disorders as Predictors of Substance Use Initiation Among African American Youth.

Journal of studies on alcohol and drugs - 1 Jul 2025

Sosnowski David W, Rabinowitz Jill A, Feder Kenneth A, Strickland Justin C, Hancock Dana B, Uhl George R, Ialongo Nicholas S, Maher Brion S

Abstract excerpt

OBJECTIVE: Despite adverse health consequences associated with early substance use initiation, less is known about the influence of genetic risk on initiation and environmental characteristics that may moderate these associations, particularly among African Americans. We examined whether genetic risk for alcohol use disorder, cannabis use disorder, and nicotine dependence is associated with age at initiation of...

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Identifiers

PMID: 40577074
DOI: 10.15288/jsad.23-00397
PMCID: PMC12315097

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