Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance of HEK-293 and COS-7 cell lines to oxidative stress as a model of metabolic response

12 Jun 2025

Abstract excerpt

Oxidative stress (OS), arising from an imbalance between reactive oxygen species (ROS) production and antioxidant defenses, plays a pivotal role in cellular dysfunction and the pathogenesis of numerous diseases. This study evaluates the impact of oxidative stress induced by hydrogen peroxide on the metabolomic profiles of the human embryonic kidney (HEK-293) and African green monkey kidney (COS-7) cell lines....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Biochemical effects in animals
Share to Redox biology and oxidative stress

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40574879
DOI: 10.3389/abp.2025.14164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance of HEK-293 and COS-7 cell lines to oxidative stress as a model of metabolic responsePMID 40574879Read ↗

1H NMR spectroscopic characterisation of HepG2 cells as a model metabolic system for toxicology studiesSemantic proximity Read ↗

An integrated proteomics and metabolomics analysis of methylglyoxal-induced neurotoxicity in a human neuroblastoma cell lineSemantic proximity Read ↗

Observation of the impact of reactive oxygen species-inducers on the metabolomes of pulmonary artery smooth muscle cells and retinal pigment epithelial cellsSemantic proximity Read ↗

Molecular Hydrogen Enhances Proliferation of Cancer Cells That Exhibit Potent Mitochondrial Unfolded Protein ResponseSemantic proximity Read ↗

Antioxidants successfully reduce ROS production in propionic acidemia fibroblasts.Semantic proximity Read ↗

A genetically encoded tool to increase cellular NADH/NAD <sup>+</sup> ratio in living cellsSemantic proximity Read ↗

Probing the Hidden Role of Mitochondrial DNA Damage and Dysfunction in the Etiology of Aristolochic Acid NephropathySemantic proximity Read ↗

Papillary renal cell carcinomas rewire glutathione metabolism and are deficient in anabolic glucose synthesisSemantic proximity Read ↗

Biochemical response of human endothelial and fibroblast cells to silver nanoparticlesSemantic proximity Read ↗

Bacterial Responses to Glyoxal and Methylglyoxal: Reactive Electrophilic SpeciesSemantic proximity Read ↗

In Vitro to In Vivo Concordance of Toxicity Using the Human Proximal Tubule Cell Line HK-2Semantic proximity Read ↗

Cell Culture Models of Oxidative Stress and Injury in the Central Nervous SystemSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.